Food allergies are on the rise - but new treatments are on the horizon
It’s an exciting time for the allergy field, experts say. Here’s what to know about what causes food allergies—and the new research that may help us cope with them.
Parents Can Reduce a Child's Peanut Allergy Risk with These Steps. Most Don't Know Them
Many parents don’t know the steps they can take to reduce the risk of their child developing a peanut allergy, five years after new prevention guidelines emerged, according to a new report. In 2017, the National Institutes of Health recommended parents expose their infants to peanuts as young as 4 months old to prevent peanut allergies.
Validation of inducible basophil biomarkers: Time, temperatureand transportation
Upregulation of basophil surface markers CD63 and CD203c uponexposure to allergens was first shown almost two decades ago(Sainte-Laudy et al., 1998). The strong correlation between theseinducible biomarkers and outcomes of food allergen challenge isproving to be a valuable clinical tool (Czechowska et al., 2019; Koplinet al., 2019; Santos et al., 2014).
Re-visiting the stability of inducible biomarkers on basophils
Upregulation of basophil surface CD63 and CD203c on exposure to allergens was first shown almost two decades ago. The strong correlation between these inducible biomarkers with outcomes of food allergen challenge is proving to be a valuable clinical tool. Requirements for fresh whole blood and reports on the time sensitivity and stability of whole blood in the assay have limited its clinical use.
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