Re-visiting the stability of inducible biomarkers on basophils

Upregulation of basophil surface CD63 and CD203c on exposure to allergens was first shown almost two decades ago. The strong correlation between these inducible biomarkers with outcomes of food allergen challenge is proving to be a valuable clinical tool. Requirements for fresh whole blood and reports on the time sensitivity and stability of whole blood in the assay have limited its clinical use.

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